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5 Specific enzymes in intracellular lysosomes or tumor microenvironments can selectively break the linker, for example, proteases in lysosomes hydrolyzing peptide bonds contained in dipeptide or tetrapeptide linkers, glycosidases hydrolyzing -glucuronides and -galactosides, phosphatases hydrolyzing phosphoesters and pyrophosphates, and sulfatases hydrolyzing sulfates

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Acknowledgments This study was supported by the National Science Centre in Poland (2014/15/B/NZ7/00893)

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10.1016/j.psychres.2020.113471 CrossRef Google Scholar View reference in article 3

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